Second positive case of chronic wasting disease confirmed in Indiana Friday, February 21, 2025 The Indiana Department of Natural Resources (DNR) has confirmed Indiana’s second positive case of chronic wasting disease (CWD). CWD is a neurological disease that affects deer, resulting in their eventual death. The positive, wild white-tailed deer was a 2.5-year-old male harvested in Posey County. CWD has been detected in wild deer in 36 states, including all states bordering Indiana. During the 2025-2026 deer hunting season, DNR will enhance its surveillance efforts in Posey County and the surrounding counties to determine the extent of disease in this area. This will allow biologists to develop a targeted response based on the prevalence of CWD in this part of Indiana. CWD testing will be voluntary for hunters in this area.